News & Events

MonolixSuite 2020 advent calendar

on 28 November 2019

Discover one cool new MonolixSuite feature each day!

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MonolixSuite 2020 is coming!

In Sycomore, in the comparison tab, it is possible to define a reference project and see the objective fonction of the other projects compared to this reference project.

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MonolixSuite 2020 is coming!

Two new cool preferences are available. We are providing a dark theme and also the possibility to zoom and unzoom.

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MonolixSuite 2020 is coming!

In PKanalix, it will be possible to filter the summary by acceptance criteria and split it by categorical covariates and occasions.

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MonolixSuite 2020 is coming!

In PKanalix, it will be possible to define several partial AUCs.

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MonolixSuite 2020 is coming!

The simulations used in the VPC will be available in the result folder,
to allow replotting elsewhere with different binning for instance.

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MonolixSuite 2020 is coming!

It will be possible to filter the data used for analysis in Monolix, by selecting rows or ids
corresponding to some criteria, and of course combining several rules.

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MonolixSuite 2020 is coming!

The graphical user interface has been modernized
and each application has now its own color.

 

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MonolixSuite 2020 is coming!

A new setting will allow to set a maximum number of iterations for the task estimating the Conditional distribution.

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MonolixSuite 2020 is coming!

The simulation application Simulx has now a GUI! It is possible to define base elements (parameters,
treatments, covariates, …) and choose which ones to use for the trial simulation.

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MonolixSuite 2020 is coming!

Monolix runs can be imported into Simulx. This automatically reads the model, estimated pop
parameters, EBEs, covariates from the data set, etc, which can be reused for simulations.

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MonolixSuite 2020 is coming!

A PKanalix run can be imported into Simulx to reuse the model and
estimated parameters for simulation of new dosing regimens for instance.

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MonolixSuite 2020 is coming!

Simulation results are displayed as interactive plots with options to split, color or filter.

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MonolixSuite 2020 is coming!

The definition of treatment elements is very flexible: via external files, vectors or regular sequences
(which can be repeated in cycles). The dose can be scaled by a covariate or missed with a given probability.

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MonolixSuite 2020 is coming!

Simulation outputs can be post-processed into outcomes (e.g is individual PK relative to
baseline in the target) and endpoints (e.g percentage of individuals in the target for each arm).

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MonolixSuite 2020 is coming!

Mlxplore will be merged into Simulx, which will have tab dedicated to model exploration
with sliders to play with the parameters but also with the dosing regimen characteristics.

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MonolixSuite 2020 is coming!

It will be possible to create new covariates for stratification of the plots and results without modifying the dataset, such as the number of doses received by each individual.

 

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MonolixSuite 2020 is coming!

There will be an option to visualize the data as trend lines with means and standard deviations computed on bins

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MonolixSuite 2020 is coming!

Objective function and BIC criteria will be available in the CA results table for individual comparisons.

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MonolixSuite 2020 is coming!

In Pkanalix, new NCA settings will allow to choose the parameters displayed in the results table.

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MonolixSuite 2020 is coming!

PKanalix will have individual fits plots for the NCA, which can be stratified, personalized and exported.

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MonolixSuite 2020 is coming!

The convergence assessment will have a summary of estimated values across runs.

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MonolixSuite 2019 is coming!

In addition to the summary of the conditional mode and the conditional mean,
all the individual parameters are displayed along with the covariates.
In addition, it is possible to sort.

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MonolixSuite 2020 is coming!

Selecting items in the plots will be easier

Jonathan CHAUVINMonolixSuite 2020 advent calendar