PAGE MonolixSuite Workshop
“Population PKPD Modeling & Simulation with the Monolix Suite”
June 6 & 7, 2016 Lisbon, Portugal.
Overview
A 2 days workshop on the Monolix Suite will be given by Marc Lavielle on the 6th and 7th of june. The course is designed for both beginners and advanced modellers.
Attendants can choose to attend either both days, Day 1 only or Day 2 only:
- Day 1 will provide a complete presentation of how to use Monolix for modelling, population analysis and parameter estimation. It covers basic and standard PKPD modelling as well as advanced modelling features.
- Day 2 will provide training on Simulx, a new clinical trial simulator for the simulation and visualization of longitudinal data and virtual patient populations. Simulx is now available as a standalone user-friendly, graphical application, and can also be used within R as a powerful simulation R package thanks to its combination with mlxR, a DDMoRe-sponsored library developed by Inria which contains several R functions for advanced clinical trial simulations. Finally the course will present complete workflows for modelling, exploration and simulation with the full Monolix Suite (Monolix, Mlxplore, Simulx)
Students and academics have access to free, renewable licenses of MonolixSuite. Industry participants will be provided a three months license of a full-featured version of MonolixSuite.
Links
Monolix Suite: www.lixoft.com – mlxR: simulx.webpopix.org
Prerequisites
Basics of population PK-PD modelling.
Instructor
Marc Lavielle
Course Agenda
Day 1: Monolix
9:00 | Introduction to Monolix and Mlxtran | |
10:30 | Coffee/Tea Break | |
11:00 | Hands on 1 PKPD modelling | |
12:00 | Lunch | |
13:00 | The SAEM algorithm | |
13:30 | Advanced features: IOV, BLQ data | |
14:30 | Modelling categorical, count and time-to-event data models | |
15:30 | Coffee/Tea Break | |
16:00 | Hands on 2 Mixture models and model mixtures | |
17:00 | End of Day 1 |
Day 2: Simulx and modelling/estimation/simulation workflow
9:00 | Introduction to Simulx | |
9:30 | Simulation of continuous data models | |
10:00 | Simulation of PK models | |
10:30 | Coffee/Tea Break | |
11:00 | Hands on 1 simulation of PK models | |
12:00 | Lunch | |
13:00 | Simulation of categorical, markov and count data models | |
13:30 | Simulation of time-to-event and joint models | |
14:00 | Simulation of advanced statistical models (IOV, categorical covariates, hierarchical models) | |
14:30 | Clinical Trial Simulation with Simulx | |
15:00 | mlxR library for using Simulx with R | |
15:30 | Coffee/Tea Break | |
16:00 | Hands on 2 complete workflow for PKPD models using the Monolix Suite | |
17:00 | End of Day 2 |
Price per person
Industry: 900€ (1 day only 600€) – Academy: 450€ (1 day only 320€) – Student: 290€
+ 200€ if registration after May 4th, 2016
Location
Lisbon Marriott Hotel
Avenida dos Combatentes, 45, 1600-042 Lisbon, Portugal
Registration