Simulx is an easy, efficient and flexible application for clinical trial simulations

Fast and easy to use with intuitive GUI

Our solutions are designed for ease of use. Simulx can be used via a graphical interface. This means less programming for you and more focus on exploring different treatments and effects of model parameters on a typical individual and/or simulating a clinical trial using a population of individuals in one or several groups with specific treatment or features. All the results are plotted and easy interpretable.

High flexibility in building scenarios

The interface allows an amazing flexibility to be able to simulate any scenario. You can define any population, any treatment, any configuration in a few clicks. Clinical trial design has never been so simple.

Advanced Statistical Methods

Outcomes and endpoints can be defined in the dedicated section. It provides a simple and efficient comparison between groups in the good statistical framework.

Guarantee productivity and quality

Efficient C++ solver package, standardized model language with Mlxtran, PK/PD, TMDD, … model libraries and integrated software all contribute to better productivity and quality. You can make your simulation from scratch or use a Monolix project.

Key features


Optimal environment to build and analyze simulation scenarios

  • Definition – create easily new exploration and simulation elements (parameters, treatments, outputs, covariates, etc.) of different types using built-in methods or external tables
  • Exploration – analyze in real time different treatments and effects of model parameters by simulating a typical individual; create several exploration groups, overlay experimental data and send a scenario in a single click to a clinical trial simulation
  • Simulation – simulate clinical trials using a population of individuals in one or several groups with specific treatment, individual characteristics or measurement times; use flexible post-processing tools, and get immediate feedback in intuitive exportable tables and interactive plots.

Outputs and plots

All simulation outputs are displayed in sortable and formatted tables easy to copy in any document and are exported in the result folder in an R-compatible format. Interactive plots are also automatically generated for straightforward interpretation of the results.

R API to automate your process

All steps performed in Simulx can be run from R with the LixoftConnectors package. What you have done once intuitively in the interface in a specific scenario can be generalized to a script automating the process for any other simulation or design optimization.

Our solutions are designed for ease of use. Simulx can be used via a graphical interface or R for powerful scripting. This means less programming for you and more focus on exploring models and pharmacology to deliver in time to your customers. The interface is simple with several steps to go through all your project. A dedicated web site for Simulx documentation is proposed here.

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