Tumor growth and tumor growth inhibition modeling workshop

Lixoft is running a 1 day hands-on workshop on tumor growth and tumor growth inhibition modeling with the MonolixSuite on Tuesday the 9th of June.
A variety of ODE-based models have been published to describe data of longitudinal tumor size. This workshop will provide an overview of the most general ones and their inclusion in a modular library, and discuss guidelines for the modelling of tumor growth data.
It will alternate lectures and hands-on sessions, using real dataset examples to show how to model tumor growth data, including how to choose the model from the library, estimate the parameters and diagnose the model, as well as combining tumor growth data with PK measurements or time-to-event data such as survival.

No prior experience of the MonolixSuite is required. Temporary licenses for the MonolixSuite will be provided.

Agenda:

[AM] Tumor growth inhibition concepts:

Introduction to tumor growth and tumor growth inhibition modeling concepts, presentation of the usual models and their underlying assumptions, and different ways to encode the treatments
Hands-on: exploration of different tumor growth inhibition models using Simulx
Guidelines for the choice of a model depending on the data
Demo: setup of a tumor growth model in Monolix, model estimation and diagnosis

[PM] Applications

Hands-on: development of a tumor growth inhibition model on a real data set, and use of the model to simulate new simulations
Advanced cases: Joint model of tumor growth with survival analysis and dropout, …

Instructor

Dr Pauline Traynard joined Lixoft in 2017 as Applications Manager. She has a multidisciplinary background focusing on computational and systems biology. After a double engineering degree specializing in computational biology from Ecole Polytechnique and MINES ParisTech (Paris, France) obtained in 2012, she applied different mathematical formalisms to model biological rhythms as part of her PhD studies at INRIA and IBENS Paris, and prostate cancer as a postdoctoral fellow in Institut Curie.

Price per person

Industry: 600€ – Academy: 300€ – Student: 150€
+ 100€ if registration after May 4th, 2020
The prices are VAT exempted, it should be added if applicable.

Location

To be defined.

Tumor growth and tumor growth inhibition modeling workshop registration

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Workshop(s) you wish to attend*

Introductory course on modeling with Monolix (Monday 27)

NCA, BE and beyond with PKanalix (Tuesday 28, afternoon)

Simulations with Simulx (Tuesday 28, morning)

Advanced modeling with Monolix (Tuesday 28)

TGI modeling with MonolixSuite (Tuesday 28)

TMDD modeling with MonolixSuite (Tuesday 28)

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I acknowledge that this is an in-person workshop taking place in Ljubljana and that online attendance is not possible.

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News & Events

Tumor growth and tumor growth inhibition modeling workshop @Page2020 (Ljubljana, Slovenia, Tuesday June 9th, 2019)